Akasha was once the queen of the Nile (she has a bit in common with the Egyptian goddess Isis), and it's unwise to rile her now that she's had 60 centuries of practice being undead. She is so peeved about male violence that she might just have to kill most of them. And she has her eye on handsome Lestat with other ideas as well.
The story of "story" of creation for vampires is so different in Anne Rice's world, much more different then anybody else's view of it. The story of Akasha and Enkil, being the rulers of Egypt and having a curse placed on them, is very original. That vampirism was an accident caused by spirits entering Enkil's body while he was stabbed and dying is very good work by the imagination of Anne Rice. I've heard many theories of how they were created, from the typical Vlad the Impaler stories, to there being a freak accident on Atlantis before it disappeared into the ocean. I like this theory the best though.
While this wasn't my favourite of the Vampire Chronicles, it certainly was one of the best. In fact, most of the series is excellent, except for the newer Vampire Tales, which are associated with the Chronicles, an extention of those stories actually.